MKSAP Questions of the Week

Hematology Oncology Question 48

A 63-year-old man is evaluated for severe mid-upper back pain following a minor fall 1 day ago. He also notes progressive fatigue of 6 months' duration and a 6.8-kg (15 lb) weight loss. Medical history is notable for an 80-pack-year smoking history, although he is currently a nonsmoker. What is the most appropriate diagnostic test to perform next?

Publish date: 08/15/2019

Infectious Diseases Question 90

A 25-year-old man is evaluated in follow-up after HIV testing. He states he has sex with other men and usually uses condoms. He had a negative HIV test result 1 year ago. What is the most appropriate next step in management?

Publish date: 08/08/2019

Nephrology Question 39

A 25-year-old man is evaluated for dark-colored urine for 2 days, swelling of the face and hands for 1 day, and severe headaches this morning. He reports having an upper respiratory tract infection 1 week ago with fever, sore throat, and swollen glands, but had otherwise felt well. What is the most likely diagnosis?

Publish date: 08/01/2019

General Internal Medicine Question 111

A 52-year-old man is evaluated for the sudden onset of erectile dysfunction that has persisted for 6 months. He reports having erections that are inadequate for vaginal penetration. What is the most likely cause of this patient's erectile dysfunction?

Publish date: 07/25/2019

Rheumatology Question 94

A 74-year-old woman is evaluated during a follow-up visit for polymyalgia rheumatica diagnosed 8 weeks ago after developing shoulder and hip girdle pain and morning stiffness. Symptoms resolved on prednisone, 15 mg/d. She feels well and reports no headache, jaw claudication, visual changes, or recurrence of myalgia or stiffness. What is is the most appropriate management at this time?

Publish date: 07/18/2019

Neurology Question 9

A 26-year-old woman is evaluated for a 10-year history of recurrent episodes of acute-onset feelings of fear and anxiety. These episodes initially occurred approximately four times per year but for the past 3 months have been occurring once or twice per month, especially when she is under stress. What is the most likely diagnosis?

Publish date: 07/11/2019

Rheumatology Question 36

A 61-year-old man is evaluated for a 10-month history of generalized weakness. He reports no pain or myalgia. History is significant for hypercholesterolemia treated with a stable dose of simvastatin for the past 3 years. On physical examination, temperature is normal, blood pressure is 138/74 mm Hg, pulse rate is 70/min, and respiration rate is 16/min. What is the most likely diagnosis?

Publish date: 07/03/2019

Dermatology Question 26

A 52-year-old woman is evaluated for a 1-month history of a spreading rash on her back, chest, and arms. She has been using over-the-counter topical glucocorticoids without relief. She does not have any other associated symptoms and otherwise feels well. What is the most likely diagnosis?

Publish date: 06/27/2019

Endocrinology Question 23

A 40-year-old woman is evaluated for amenorrhea of 4 months' duration. She has had weight gain, facial hair, alopecia, and debilitating fatigue. Her medical history is significant for psoriasis. She seems to be gaining weight in her face, abdomen, and neck. She also bruises easily. Her only medication is clobetasol for psoriasis. What is the most likely diagnosis?

Publish date: 06/12/2019

Gastroenterology Question 92

A 25-year-old man is evaluated in follow-up after recently testing positive for hepatitis B surface antigen. He underwent testing as part of the immigration process from Somalia. Two other siblings also have hepatitis B virus (HBV) infection. What is the most appropriate management?

Publish date: 06/05/2019

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