Hematology/Oncology Question 10

A 28-year-old woman is evaluated for a 1-week history of progressive dyspnea and fatigue. She was diagnosed with Hodgkin lymphoma 2 months ago and is receiving chemotherapy with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). She takes no other medications.

On physical examination, temperature is 36.8 °C (98.2 °F), blood pressure is 134/82 mm Hg, pulse rate is 105/min, and respiration rate is 16/min. Oxygen saturation is 98% breathing ambient air. Conjunctival pallor is noted but no scleral icterus. The lungs are clear to auscultation, and the cardiac examination is normal. The remainder of the examination is unremarkable.

A peripheral blood smear shows pancytopenia but is otherwise unremarkable.

Which of the following is the most appropriate erythrocyte transfusion product for this patient?

A  Leukoreduced

B  Leukoreduced, cytomegalovirus-negative

C  Leukoreduced, irradiated

D  Leukoreduced, washed

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