General IM Q44

During a routine health examination, a patient asks about an article that recommended avoiding statin therapy because of the risk for memory loss. The findings were based on cross-sectional data analysis of a well-validated national health survey, which was conducted by random sampling of patients according to zip code of residence. The analysis showed that patients who self-reported memory loss were more likely to also report having taken statin drugs (odds ratio, 1.8; 95% CI, 1.2-2.7; P = 0.046).

Which of the following is the most likely threat to the validity of this study?

A Confounding

B Selection bias

C Self-reported data

D Statistical significance

Choose an Answer Above

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