Gastroenterology and Hepatology Q29

A 35-year-old woman is evaluated for constipation. She reports passage of hard stool every 3 to 4 days and associated bloating. Her symptoms have been present for more than 10 years and have progressed gradually. Trials of over-the-counter fiber supplementation and polyethylene glycol worsened the bloating, prompting discontinuation. Senna tea was ineffective. Bisacodyl caused abdominal cramping. She is otherwise healthy and currently takes no medication.

On physical examination, vital signs and other findings are normal.

Which of the following is the most appropriate treatment?

Rifaximin
 

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