Dermatology Q 1

A 63-year-old man is evaluated for a skin eruption that is itchy and worsening for the past several weeks. Medical history is unremarkable, and he takes no medications.

On physical examination, vital signs are normal. There are tense bullae on an erythematous base and scattered erosions on the trunk and extremities.

Which of the following is the most appropriate diagnostic test to perform next?

A Biopsy of lesional skin for direct immunofluorescence

B Biopsy of lesional skin for histology

C Biopsy of lesional skin for histology and perilesional skin for direct immunofluorescence

D Biopsy of perilesional skin for histology and direct immunofluorescence

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